What Is Cystic Fibrosis?

Cystic fibrosis (CF) is an inherited disease of your mucus and sweat glands. It primarily affects your lungs, pancreas, liver, intestines, sinuses, and sex organs.

Normally, mucus is watery. It keeps the linings of certain organs moist and prevents them from drying out or getting infected. But in CF, an abnormal gene causes mucus to become thick and sticky.

The mucus builds up in your lungs and blocks the airways. This makes it easy for bacteria to grow and leads to repeated serious lung infections. Over time, these infections can cause serious damage to your lungs.

The thick, sticky mucus can also block tubes, or ducts, in your pancreas. As a result, digestive enzymes that are produced by your pancreas cannot reach your small intestine. These enzymes help break down the food that you eat. Without them, your intestines cannot absorb fats and proteins fully.

As a result:

- Nutrients leave your body unused, and you can become malnourished.
- Your stools become bulky.
- You may not get enough vitamins A, D, E, and K.
- You may have intestinal gas, a swollen belly, and pain or discomfort.

The abnormal gene can also cause your sweat to become extremely salty. As a result, when you perspire, your body loses large amounts of salt. This may upset the balance of minerals in your blood and potentially lead to a heat emergency.

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